The driver of a car that Circleville police stopped pursuing later caused a three-vehicle crash Wednesday afternoon on Route 23, killing herself and injuring six others in another vehicle, authorities said.

Susan Frazier, 61, of Circleville died in the crash which occurred at 12:24 p.m., about two miles north of Chillicothe in Ross County, the Ohio Highway Patrol said.

Frazier was driving the wrong way, going southbound in the northbound lanes of Route 23 when the crash occurred, the patrol said.

She sideswiped a car driven by Candice Cain, 46, of University Park, Illinois, which had two passengers. They were not injured.

Then, Frazier’s car crashed into an SUV driven by Thomas Laciano, 49, of Concord, North Carolina. Laciano’s 46-year-old wife, Allison and four juveniles were passengers, the patrol said.

The two vehicles came to rest in the median. Frazier’s vehicle burst into flames.

Frazier was pulled from the vehicle. She was later pronounced dead at Adena Regional Medical Center in Chillicothe, the patrol said,

The six occupants in the Laciano vehicle were initially transported to the Adena center for treatment of non-life-threatening injuries. Allison Laciano was later transported to OhioHealth Grant Medical in Columbus and three of the four juveniles were taken to Nationwide Children’s Hospital for further treatment.

Circleville police in Pickaway County had first noticed Frazier’s vehicle just before noon on Route 23 and pursued it before terminating the chase. It was not clear why Circleville police pursued Frazier’s vehicle.